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Tufts Public Health

Alysse G. Wurcel

Assistant Professor of Medicine

Alysse G. Wurcel

Assistant Professor of Medicine

Phone ​617-636-7010
Campus: Boston


Dr. Wurcel completed her undergraduate education at Tufts University. She is a graduate of University of Pennsylvania School of Medicine and received a Masters in Clinical Research from the Sacker School of Graduate Biomedical Sciences at Tufts University School of Medicine. In addition to her faculty position in the Department of Geographic Medicine and Infectious Diseases, she is an Assistant Professor in the Department of Community Medicine and Public Health at the Tufts University School of Medicine. She has a weekly HIV/HCV co-infection clinic and also treats people with HIV and HCV mono-infection. Once a month in her co-infection clinic, she sees patients with Dr. Hannah Lee of the GI department. Her research interests include treatment of Hepatitis C Virus in people considered "tough to treat" including people who inject drugs (PWID), people in the criminal justice system and people with HIV (PLWH). She is the co-investigator of the Tufts REACTs Study (Responds to the Epidemic of hepatitis C Together), a mixed methods project aimed at assessing HCV treatment readiness in young PWID. This study was awarded funding through the Tufts Institute for Innovation in 2015. She is the PI on a Bristol-Myers Squibb study in a clinical trial of HIV medication called an HDAC Inhibitor. Tufts Medical Center is the only hospital in Boston to offer this clinical trial. She also has funding to conduction quality improvement studies on increasing annual HCV antibody testing in PLWH who were Hepatitis C Antibody negative on entry into HIV care. Dr. Wurcel was recently named to the Tufts Institute of Innovation Affiliates. Affiliates are active members of the TII community they have access to TII lab space, are invited to participate in TII Project Review meetings, and can extend their three-year appointment after its expiration by securing external funding for their projects.


  • ​University of Pennsylvania School of Medicine;
  • Massachusetts General Hospital;
  • Columbia University Medical Center;
  • Tufts Medical Center

Research interests

Nutrition and Infectious Diseases

Research synopsis

Infectious diseases, HIV, hepatitis C, HIV pre-exposure prophylaxis, sexually transmitted diseases


Taylor LE, Foont JA, DeLong AK, Wurcel, A, Linas BP, Chapman SC, Maynard MA, Cu-Uvin S, Mayer KH. The Spectrum of Undiagnosed Hepatitis C Virus Infection in a U.S. HIV Clinic. AIDS Patient Care and STDS. Volume 28, Number 1, 2014.

Wurcel,AG. To whom shall I tell my grief? Am J Kidney Dis. November 2013;62(5):xxv-xxvi.

Sung S*, Wurcel AG*, Whittier S, Kulas K, Kramer LD, Flam R, et al. Powassan meningoencephalitis, New York City, USA. Emerg Infect Dis [Internet]. 2013 Sep (*co-first authors).

McNairy M, Wurcel A, Huang F, Daly J. Health care workers in Africa access a broad range of topics using evidence-based online medical information. Global Public Health Journal May 2012. PMID #22621407

Ancuta P, Kamat A, Kunstman KJ, Kim EY, Autissier P, Wurcel A, Zaman T, Stone D, Mefford M, Morgello S, Singer EJ, Wolinsky SM, Gabuzda D. Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. PLoS ONE. 2008 Jun 25;3(6):e2516.

Corey KE, Ross AS, Wurcel A, Schulze Zur Wiesch J, Kim AY, Lauer GM, Chung RT. Outcomes and treatment of acute hepatitis C virus infection in a United States population. Clin Gastroenterol Hepatol. 2006 Oct; 4(10):1278-82.