Neuroscience Faculty

Research/Areas of Interest: My current interests are the physiology and pharmacology of channels belonging to the Cys-loop ligand-gated ion channel (LGIC) superfamily. These channels are associated with several neuropyschiatric disorders including epilepsy, anxiety, schizophrenia, depression, substance abuse and stroke. We use the patch-clamp technique to record and measure ion channel function of the following LGICs.

Research/Areas of Interest: The principal goal of my research is to understand how neurotransmission contributes to the function of neuronal networks. Neurotransmission is the most basic unit of neuronal communication. Disruption of the basic features of neurotransmission is associated with many neurological diseases. My lab aims to understand how specific properties of synaptic function contribute to network activity, and how changes in neurotransmission are involved in the pathology of disease states such as epilepsy and traumatic brain injury. We are specifically interested in astrocyte glutamate uptake, astrocyte/neuron interactions, GABAergic interneuron development, and metabolic control of neuronal activity. Using advanced neurotransmitter imaging, electrophysiological techniques, and more, my lab aims to answer questions about how neuronal network function is shaped by some of the most basic parameters of neurotransmission. We hope to contribute new understanding and novel therapies to treat epilepsy, traumatic brain injury, and other devastating neurological diseases.